바이오스토리

CUSTOMER

국내 바이오 업계의 21세기 선두주자

[dcchemicals] STM2457

작성자 관리자 작성일 2021-10-29
조회수 3,480회 댓글 0

본문

  카탈로그 NO :

DC53045

  제품 생산일 :

  원산지 :

미국

  생산기업 :

dcchemicals

  특징 및 규격

 

바이오스토리에서 dcchemicals 브랜드 직수입하고 있습니다.

많은 문의 부탁드립니다^^

 

STM2457

Cat. No.: DC53045

Field of application

STM2457 is in stock, and we can ship it immeidately. STM2457 is a potent inhibitor of METTL3/METTL14 catalytic activity with IC50 of 16.9 nM, Kd of 1.4 nM, respectively. STM2457 is highly specific for METTL3 and shows significant anti-leukaemic effect.

 

Cas No.:

2499663-01-1

Chemical Name:

STM2457

Synonyms:

STM2457;STM-2457;STM 2457

SMILES:

C1=CC=CC2=NC(C(=O)NCC3N=C4C=CC(CNCC5CCCCC5)=CN4C=3)=CC(=O)N12

Formula:

C25H28N6O2

M.Wt:

444.23

Purity:

>98%

Sotrage:

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Publication:

Small molecule inhibition of METTL3 as a strategy against myeloid leukaemia--Nature-Eliza Yankova, Wesley Blackaby-Published: 26 April 2021

Copyright (c) 2019 by BIO STORY. All Rights Reserved.